MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F10%3A%230001053" target="_blank" >RIV/65269705:_____/10:#0001053 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/10:#0000119 RIV/00209805:_____/10:#0000134 RIV/00216224:14110/10:00051702
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients
Original language description
MicroRNAs are endogenously expressed regulatory noncoding RNAs. Previous studies showed altered expression levels of several microRNAs in glioblastomas. In this study, we examined the expression levels of selected microRNAs in 22 primary glioblastomas and six specimens of adult brain tissue by real-time PCR method. In addition, we examined methylation status of MGMT promoter by methylation-specific real-time PCR, as this has been shown to be a predictive marker in glioblastomas. MGMT methylation statuswas not correlated with response to concomitant chemoradiotherapy with temozolomide
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/NS9875" target="_blank" >NS9875: Mechanisms of immunoresistance in glioblastoma</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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