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Soluble ST2 levels in patients with cardiogenic and septic shock are not predictors of mortality

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F12%3A%230001643" target="_blank" >RIV/65269705:_____/12:#0001643 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/12:#0000921 RIV/00216224:14110/12:00064953

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Soluble ST2 levels in patients with cardiogenic and septic shock are not predictors of mortality

  • Original language description

    BACKGROUND: Soluble ST2 (sST2) is an interleukin-33 receptor. sST2 was found to be an independent prognostic factor in patients with myocardial infarction, sepsis and heart failure. OBJECTIVES: To assess sST2 levels in patients with cardiogenic shock (CS) and septic shock (SS), and to evaluate the prognostic value of sST2 for short-term mortality. METHODS: The present prospective observational study evaluated 32 patients with CS, 17 patients with SS and 61 patients with ST segment elevation myocardial infarction (STEMI )(control group). Samples of serum were collected eight times and the follow-up time was three months. RESULTS: sST2 levels were elevated from admission in SS patients relative to patients with CS and STEMI, who exhibited peak sST2 levels 24 h after admission. On admission, CS patients had a median (5th percentile; 95th percentile) sST2 level of 62.5 pg/mL (8.3 pg/mL; 315.8 pg/mL) and SS patients had a median sST2 level of 216.4 pg/mL (46.8 pg/mL; 364.4 pg/mL). ROC analy

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS9894" target="_blank" >NS9894: Role of SIRS, NO and oxydative stress in the development of shock state and mitochondrial dysfunction as the basis of multiorgan failure</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Experimental & Clinical Cardiology

  • ISSN

    1205-6626

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CA - CANADA

  • Number of pages

    5

  • Pages from-to

    205-209

  • UT code for WoS article

    000312820300011

  • EID of the result in the Scopus database