Nanotechnology and mesenchymal stem cells with chondrocytes in prevention of partial growth plate arrest in pigs

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F12%3A%230001650" target="_blank" >RIV/65269705:_____/12:#0001650 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/12:00383204 RIV/67985904:_____/12:00383204 RIV/62157124:16170/12:43871420
Result on the web
<a href="http://dx.doi.org/10.5507/bp.2012.041" target="_blank" >http://dx.doi.org/10.5507/bp.2012.041</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2012.041" target="_blank" >10.5507/bp.2012.041</a>

Result language
angličtina
Original language name
Nanotechnology and mesenchymal stem cells with chondrocytes in prevention of partial growth plate arrest in pigs
Original language description
Introduction: This study describes the results achieved using a combination of allogeneic mesenchymal stem cells (MSCs) with chondrocytes (CHC) and a new scaffold consisting of type-I collagen and chitosan nanofibers in the prevention of partial growth plate arrest after iatrogenic injury in pigs. Material and methods: The miniature pig was selected as an experimental model to compare the results in the left femoral bones (MSCs and CHC in scaffold transplantation into the iatrogenic partial distal growth plate defect) and right femoral bones (scaffold alone transplantation). The experimental group consisted of 10 animals. Bone marrow from os ilium as the source of MSCs was used. A porous cylinder consisting of 0.5% by weight type-I collagen and 30% byweight chitosan, was the optimal choice. The length of the bone and angular deformity of distal femur after the healing period was measured and the quality and structure of the newly formed cartilage was histologically examined. Results:
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc,
ISSN
1213-8118
e-ISSN
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Volume of the periodical
156
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
7
Pages from-to
128-134
UT code for WoS article
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EID of the result in the Scopus database
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