Superiority of SPECT/CT over planar I-123-mIBG images in neuroblastoma patients with impact on Curie and SIOPEN score values

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F16%3A00065796" target="_blank" >RIV/65269705:_____/16:00065796 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/16:00091987

Result on the web

<a href="https://nuk.schattauer.de/inhalt/archivestandard/issue/2381/manuscript/25718.html" target="_blank" >https://nuk.schattauer.de/inhalt/archivestandard/issue/2381/manuscript/25718.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3413/Nukmed-0743-15-05" target="_blank" >10.3413/Nukmed-0743-15-05</a>

Result language

angličtina

Original language name

Superiority of SPECT/CT over planar I-123-mIBG images in neuroblastoma patients with impact on Curie and SIOPEN score values

Original language description

Objective: The existing most common semi quantitative systems used for neuroblastoma diagnosis include Curie and SIOPEN scores, which are based on I-123-MIBG planar scans. The purpose of our study was to find out whether a statistically significant difference exists in evaluation based on planar and SPECT/CT scans. We also compared the Curie and SIOPEN methods in terms of their use in regular practice. Patients; method: 45 patients aged 0-10 years; 213 assessments were done in total, and the Curie and SIOPEN scores were determined in each case based on planar and SPECT/CT scans. Student's T-test and the Bland-Altman plot were used for the statistical analysis. Results: Both methods demonstrated a statistically significant difference (p < 0.0001) between planar and SPECT/CT evaluation. In the group of 35 patients with neuroblastoma in clinical stages 3 and 4, in 54% of the patients SPECT/CT detected a lesion that was not visible in the planar scan. In 89% of cases, the lesion was confirmed by another imaging method (CT, MRI). In the group of 10 patients in the clinical stage 1, a difference between planar and SPECT/CT scanning was found only in one patient (10%). In the whole set, 25% patients showed a pathological finding only in soft tissues. Conclusion: We recommend to perform semiquantitative evaluation of neuroblastoma based on SPECT/CT scans, particularly in patients in clinical stages 3 and 4. It is advisable to include soft tissues in the score assessment, as well, given that only soft tissues may be involved in up to 25%

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nuklearmedizin-Nuclear Medicine

ISSN

0029-5566

e-ISSN

—

Volume of the periodical

55

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

151-157

UT code for WoS article

000381451900004

EID of the result in the Scopus database

—