Can we improve the therapy of Clostridium difficile infection in elderly patients?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F16%3A00065959" target="_blank" >RIV/65269705:_____/16:00065959 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/16:00092333 RIV/00216305:26210/16:PU121953

Result on the web

<a href="http://dx.doi.org/10.1007/s00508-016-1056-z" target="_blank" >http://dx.doi.org/10.1007/s00508-016-1056-z</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00508-016-1056-z" target="_blank" >10.1007/s00508-016-1056-z</a>

Result language

angličtina

Original language name

Can we improve the therapy of Clostridium difficile infection in elderly patients?

Original language description

Clostridium difficile infection (CDI) is becoming a serious problem predominantly in geriatric patients, who are a significant risk group. The goal of this study was to evaluate the risk factors for mortality in CDI patients and to construct a binary logistic regression model that describes the probability of mortality in geriatric patients suffering from CDI. In this retrospective study, we evaluated a group of 235 patients over 65 years of age with confirmed diagnoses of CDI, hospitalized at the Department of Internal Medicine, Geriatrics and General Practice, Brno, from January 2008 to December 2013. The examined group comprised 148 women (63 %) and 87 men (37 %). For the diagnosis of CDI, confirmation of A and B toxins in the patients' stool or an autopsy confirmation was crucial. The impact of antibiotic therapy on the increased incidence of CDI was clearly confirmed in our study group when examining patients' histories. Other risk factors included cerebrovascular disease, dementia, the presence of pressure ulcers, and immobility. Our new model consisted of a combination of the following parameters: the number of antibiotics used (from patients' history), nutritional status (Mini Nutritional Assessment short-form test), presence of pressure ulcers, and occurrence of fever. Our logistic regression model may predict mortality in geriatric patients suffering from CDI. This could help improve the therapeutic process.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

—

Project

<a href="/en/project/LO1202" target="_blank" >LO1202: NETME CENTRE PLUS</a><br>

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Wiener Klinische Wochenschrift

ISSN

0043-5325

e-ISSN

—

Volume of the periodical

128

Issue of the periodical within the volume

15-16

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

592-598

UT code for WoS article

000382676200008

EID of the result in the Scopus database

—