Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F18%3A00068534" target="_blank" >RIV/65269705:_____/18:00068534 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/18:00102797
Result on the web
<a href="https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.12371" target="_blank" >https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.12371</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ijgo.12371" target="_blank" >10.1002/ijgo.12371</a>

Result language
angličtina
Original language name
Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors
Original language description
Objective: To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. Methods: In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. Results: Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P>0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. Conclusion: CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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