Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00071145" target="_blank" >RIV/65269705:_____/19:00071145 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/19:00110557
Result on the web
<a href="https://www.prolekare.cz/casopisy/epidemiologie/2019-2-22/infekce-a-kolonizace-clostridium-difficile-u-deti-do-3-let-veku-prospektivni-srovnavaci-studie-113236" target="_blank" >https://www.prolekare.cz/casopisy/epidemiologie/2019-2-22/infekce-a-kolonizace-clostridium-difficile-u-deti-do-3-let-veku-prospektivni-srovnavaci-studie-113236</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Clostridium difficile infection and colonisation in children under 3 years of age: prospective comparative study
Original language description
Aims: Despite an increasing trend in Clostridium difficile infections (CDI) and high C difficile colonization rate especially among younger children. infants remain quite resistant to the disease. The goals of this study were to distinguish whether there exists a difference in CDI between children with or without diarrhoea, ascertain the prevalence of CDI, and assess CDI severity in children under 3 years with diarrhoea in our institution. Methods: A prospective study was conducted from May 2015 to June 2016. Children 3 years of age or younger were enrolled and into two groups. Every faecal sample was tested using a diagnostic two step screening algorithm including an immunochromatographic test and polymerase chain reaction. Results: The study enrolled 147 children with diarrhoea and 75 control patients. I he prevalence of CDI in children with diarrhoea was 2% (3/147), the prevalence of toxigenic C. difficile in the diarrhoeal group compared to the control group was 11.6 % (17/147) vs. 10.6% (8/75) (p < 0.9999). Conclusions: No significant difference was observed between infants with diarrhoea and the control group. We recommend not examining for C. difficile children not exhibiting specific risk factors.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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