Sex differences in heart rate responses to postural provocations
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00071762" target="_blank" >RIV/65269705:_____/19:00071762 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/19:00112433
Result on the web
<a href="https://www.internationaljournalofcardiology.com/article/S0167-5273(19)33952-X/pdf" target="_blank" >https://www.internationaljournalofcardiology.com/article/S0167-5273(19)33952-X/pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ijcard.2019.09.044" target="_blank" >10.1016/j.ijcard.2019.09.044</a>
Alternative languages
Result language
angličtina
Original language name
Sex differences in heart rate responses to postural provocations
Original language description
Sex differences are known in several facets of cardiac electrophysiology, mostly concerning myocardial repolarisation. In this study, heart rate and heart rate variability (HRV) responses to postural provocations were compared in 175 and 176 healthy females and males, respectively (aged 33.1 +/- 9.1 years). Two different postural provocative tests with position changes supine -> sitting -> standing -> supine and supine -> standing -> sitting -> supine (15-min standing, 10-min other positions) were performed up to 4 times in each subject. Heart rate and heart rate variability spectral indices were measured in 5-min windows before positional changes. At supine position, females had averaged heart rate approximately 5 beats per minute (bpm) faster than males and this sex difference was practically constant during the postural changes. In both sexes, change supine -> sitting and supine -> standing increased heart rate by approximately 10 and 30 bpm, respectively, with no statistical differences between the sex groups. At supine baseline, females had normalised high frequency components (nHF) of HRV approximately 7% larger compared to males (p < 0.001). While the same difference in nHF was found at sitting, the change to standing position lead to significantly larger nHF reduction in females compared to males (mean changes 22.5 vs 17.2%, p < 0.001). This shows that despite similar heart rate increase, females respond to standing by more substantial shifts in cardiac sympatho- vagal modulations. This makes it plausible to speculate that the differences in autonomic reactions to stress contribute to the known sex-differences in psychosocial responses to stressful situations and to the known difference in susceptibility to ventricular fibrillation between females and males.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Cardiology
ISSN
0167-5273
e-ISSN
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Volume of the periodical
297
Issue of the periodical within the volume
DEC 15
Country of publishing house
IE - IRELAND
Number of pages
9
Pages from-to
126-134
UT code for WoS article
000502550800030
EID of the result in the Scopus database
2-s2.0-85073166012