Novel HARDI-ZOOMit protocol detects changes in spinal cord microstructure in patients with asymptomatic non-myelopathic degenerative cervical spinal cord compression

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00071817" target="_blank" >RIV/65269705:_____/19:00071817 - isvavai.cz</a>
Result on the web
<a href="http://archive.ismrm.org/2019/3532.html" target="_blank" >http://archive.ismrm.org/2019/3532.html</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Novel HARDI-ZOOMit protocol detects changes in spinal cord microstructure in patients with asymptomatic non-myelopathic degenerative cervical spinal cord compression
Original language description
Detection of degenerative cervical spinal cord compression (DCSCC) at early stage that causes spinal cord (SC) microstructure disruption is limited when current imaging techniques are used. Early detection of damage to SC can predict symptomatic degenerative cervical myelopathy (DCM). We are presenting novel HARDI-ZOOMit protocol (High Angular Resolution Diffusion Imaging + syngo ZOOMit sequence), which is able to detect changes in microstructural diffusion MRI (dMRI) parameters (e.g. fractional anisotropy - FA, mean diffusivity - MD) in asymptomatic DCSCC. Results obtained with HARDI-ZOOMit protocol reveal higher sensitivity when compared to clinical RESOLVE (REadout Segmentation Of Long Variable Echo trains) protocol.
Czech name
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Czech description
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Project
<a href="/en/project/NV18-04-00159" target="_blank" >NV18-04-00159: Advanced magnetic resonance techniques to disclose pathophysiology and improve diagnosis and clinical management of degenerative cervical cord compression</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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