Epidemiological trends for childhood and adolescent cancers in the period 1994- 2016 in the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00071983" target="_blank" >RIV/65269705:_____/19:00071983 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/19:00113199

Result on the web

<a href="https://www.linkos.cz/files/klinicka-onkologie/466/5656.pdf" target="_blank" >https://www.linkos.cz/files/klinicka-onkologie/466/5656.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14735/amko2019426" target="_blank" >10.14735/amko2019426</a>

Result language

angličtina

Original language name

Epidemiological trends for childhood and adolescent cancers in the period 1994- 2016 in the Czech Republic

Original language description

Background: Our study aimed to evaluate incidence and mortality trends for childhood and adolescent cancers in the period 1994- 2016 in the Czech Republic. Material and methods: Data on childhood cancers, which are recorded in the Czech National Cancer Registry, were validated using a clinical database of childhood cancer patients and combined with data from the National Register of Hospitalised Patients and with data from death certificates. These validated data were used to establish cancer incidence. Data from death certificates were used to evaluate long-term trends in mortality. Incidence and mortality trends were assessed by the average annual percentage change. Results: The age-standardised incidence trend for childhood cancers (i.e. those diagnosed in patients aged 0- 19 years) showed a statistically significant slight long-term increase in the number of new cases, +0.5% annually on average (p &lt; 0.01), more specifically an increase of +0.6% in girls and a statistically insignificant decrease of MINUS SIGN 0.1% in boys. In children aged 0- 14 years, other malignant epithelial neoplasms and malignant melanomas showed the largest statistically significant average annual increase in incidence (+4.9%; p &lt; 0.01), followed by central nervous system neoplasms (+1.3%; p &lt; 0.05). Lymphomas, by contrast, showed a statistically significant average annual decrease in incidence in children aged 0- 14 years (MINUS SIGN 2.1%; p &lt;0.01). In adolescents aged 15- 19 years, other malignant epithelial neoplasms and malignant melanomas also showed a statistically significant average annual increase in incidence (+5.2%; p &lt; 0.01), followed by central nervous system neoplasms (+1.5%; p &lt; 0.05). Mortality trends showed a statistically significant long-term decrease: On average, MINUS SIGN 5.1% annually in children aged 0- 14 years (p &lt; 0.01), and MINUS SIGN 3.7% annually in adolescents aged 15- 19 years (p &lt; 0.01). Conclusion: Available data make it possible to analyselong-term trends in childhood cancer incidence and mortality.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30204 - Oncology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Klinická onkologie

ISSN

0862-495X

e-ISSN

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Volume of the periodical

32

Issue of the periodical within the volume

6

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

426-435

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85076689106