The Direct Costs of Dravet's Syndrome before and after Diagnosis Assessment
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F21%3A00074228" target="_blank" >RIV/65269705:_____/21:00074228 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/21:00120783
Result on the web
<a href="https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1718518" target="_blank" >https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0040-1718518</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/s-0040-1718518" target="_blank" >10.1055/s-0040-1718518</a>
Alternative languages
Result language
angličtina
Original language name
The Direct Costs of Dravet's Syndrome before and after Diagnosis Assessment
Original language description
The objective of this study was to estimate the direct cost before and after diagnosis assessment in patients with Dravet's syndrome (DS). The basis of the economic study was to calculate the costs of health care before and after diagnosis of DS. We retrospectively evaluated all SCN1A positive patients with phenotype of DS treated in our hospital. Statistical analyses were performed by IBM SPSS Statistics 24.0 software. After the diagnosis of DS, there was a significant decline of health care costs (-85.6%) an average of Euro29.4 +/- 26.1 monthly per patient. We estimated the monthly costs at Euro204.5 +/- 167 (median: Euro193.9, range: Euro35.5-534.4) per patient before DS diagnosis. The major cost was for hospitalization in neurological department: Euro43.3 +/- 52 (median: Euro21.9, range: Euro9.5-179.4) per patient. Minimal cost per patient per months before DS diagnosis was cost of psychological testing/care and complementary rehabilitation (0.13 and 0.6% of total cost). After DS diagnosis, the major cost was focused on nonhospitalization care of patients (64.8%), minimal (Euro0) for genetic testing and major for outpatient care (18%, mean: Euro5.3, median: Euro7). DS results in essential health care utilization and high financial burden before diagnosis elucidation caused by repeated hospitalization and extensive diagnostics tests of "epileptic encephalopathy of unknown etiology." The results of this study point out that early assessment of the diagnosis leads to significant decrease of the financial costs because of adequate therapeutic management and exclusion of redundant diagnostic testing after elucidation of correct diagnosis.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuropediatrics
ISSN
0174-304X
e-ISSN
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Volume of the periodical
52
Issue of the periodical within the volume
01
Country of publishing house
DE - GERMANY
Number of pages
6
Pages from-to
6-11
UT code for WoS article
000578772900001
EID of the result in the Scopus database
2-s2.0-85094117132