Oxidative Stress in the Brain: Basic Concepts and Treatment Strategies in Stroke

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F21%3A00075828" target="_blank" >RIV/65269705:_____/21:00075828 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/21:00124015

Result on the web

<a href="https://www.mdpi.com/2076-3921/10/12/1886" target="_blank" >https://www.mdpi.com/2076-3921/10/12/1886</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/antiox10121886" target="_blank" >10.3390/antiox10121886</a>

Result language

angličtina

Original language name

Oxidative Stress in the Brain: Basic Concepts and Treatment Strategies in Stroke

Original language description

The production of free radicals is inevitably associated with metabolism and other enzymatic processes. Under physiological conditions, however, free radicals are effectively eliminated by numerous antioxidant mechanisms. Oxidative stress occurs due to an imbalance between the production and elimination of free radicals under pathological conditions. Oxidative stress is also associated with ageing. The brain is prone to oxidative damage because of its high metabolic activity and high vulnerability to ischemic damage. Oxidative stress, thus, plays a major role in the pathophysiology of both acute and chronic pathologies in the brain, such as stroke, traumatic brain injury or neurodegenerative diseases. The goal of this article is to summarize the basic concepts of oxidative stress and its significance in brain pathologies, as well as to discuss treatment strategies for dealing with oxidative stress in stroke.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Antioxidants

ISSN

2076-3921

e-ISSN

—

Volume of the periodical

10

Issue of the periodical within the volume

12

Country of publishing house

CH - SWITZERLAND

Number of pages

12

Pages from-to

1886

UT code for WoS article

000735841100001

EID of the result in the Scopus database

2-s2.0-85119895192