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Oral azacitidine preserves favorable level of fatigue and health-related quality of life for patients with acute myeloid leukemia in remission: results from the phase III, placebo-controlled QUAZAR AML-001 trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F21%3A00075830" target="_blank" >RIV/65269705:_____/21:00075830 - isvavai.cz</a>

  • Result on the web

    <a href="https://haematologica.org/article/view/haematol.2021.279174" target="_blank" >https://haematologica.org/article/view/haematol.2021.279174</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3324/haematol.2021.279174" target="_blank" >10.3324/haematol.2021.279174</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Oral azacitidine preserves favorable level of fatigue and health-related quality of life for patients with acute myeloid leukemia in remission: results from the phase III, placebo-controlled QUAZAR AML-001 trial

  • Original language description

    The impact of Oral-AZA on patient-reported fatigue and HRQoL, a key secondary endpoint in QUAZAR AML-001, was assessed using the self-administered Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue Scale and EuroQoL EQ-5D-3L instruments. We hypothesized that Oral-AZA treatment would not meaningfully worsen fatigue or overall HRQoL from baseline, and that mean changes from baseline in fatigue and HRQoL scores in the Oral-AZA arm would be comparable (i.e., not inferior) to those in the placebo arm.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Haematologica

  • ISSN

    0390-6078

  • e-ISSN

  • Volume of the periodical

    106

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    IT - ITALY

  • Number of pages

    5

  • Pages from-to

    3240-3244

  • UT code for WoS article

    000732456400031

  • EID of the result in the Scopus database

    2-s2.0-85120738327