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The Cow's Milk-Related Symptom Score (CoMiSS((TM))): A Useful Awareness Tool

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F22%3A00076078" target="_blank" >RIV/65269705:_____/22:00076078 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/22:00127376

  • Result on the web

    <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146599/pdf/nutrients-14-02059.pdf" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9146599/pdf/nutrients-14-02059.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3390/nu14102059" target="_blank" >10.3390/nu14102059</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The Cow's Milk-Related Symptom Score (CoMiSS((TM))): A Useful Awareness Tool

  • Original language description

    The Cow&apos;s Milk-related Symptom Score (CoMiSS (TM)) was developed as a clinical tool aimed at increasing the awareness of health care professionals for the presence and intensity of clinical manifestations possibly related to cow&apos;s milk (CM) intake. This review summarizes current evidence on CoMiSS. We found twenty-five original studies, one pooled analysis of three studies, and two reviews on CoMiSS. Infants exhibiting symptoms possibly related to CM, present with a higher median CoMiSS (6 to 13; 16 studies) than apparently healthy infants (median from 3 to 4; and mean 3.6-4.7; 5 studies). In children with cow&apos;s milk allergy (CMA), 11 studies found that a CoMiSS of &gt;= 12 predicted a favorable response to a CM-free diet; however, sensitivity (20% to 77%) and specificity (54% to 92%) varied. The decrease of CoMiSS during a CM elimination diet was also predictive of a reaction to an oral food challenge to diagnose CMA. A low CoMiSS (&lt;6) was predictive for the absence of CMA. It was shown that no special training is required to use the tool in a reliable way. Intra-rater reliability was high with very low variability (intra-class correlation 0.93; 95% confidence interval 0.90-0.96; p &lt; 0.001) in repeated assessments. This review found that CoMiSS cannot be considered as a stand-alone CMA diagnostic tool, but that it is a useful awareness tool for CMA as well as for monitoring symptom improvement.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30308 - Nutrition, Dietetics

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nutrients

  • ISSN

    2072-6643

  • e-ISSN

    2072-6643

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    22

  • Pages from-to

    2059

  • UT code for WoS article

    000801799000001

  • EID of the result in the Scopus database

    2-s2.0-85129791169