Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI: Insights from the ISACS-STEMI COVID-19 Registry

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F22%3A00076603" target="_blank" >RIV/65269705:_____/22:00076603 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2077-0383/11/22/6722" target="_blank" >https://www.mdpi.com/2077-0383/11/22/6722</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcm11226722" target="_blank" >10.3390/jcm11226722</a>

Result language

angličtina

Original language name

Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI: Insights from the ISACS-STEMI COVID-19 Registry

Original language description

The so-called &quot;smoking paradox&quot;, conditioning lower mortality in smokers among STEMI patients, has seldom been addressed in the settings of modern primary PCI protocols. The ISACS-STEMI COVID-19 is a large-scale retrospective multicenter registry addressing in-hospital mortality, reperfusion, and 30-day mortality among primary PCI patients in the era of the COVID-19 pandemic. Among the 16,083 STEMI patients, 6819 (42.3%) patients were active smokers, 2099 (13.1%) previous smokers, and 7165 (44.6%) non-smokers. Despite the impaired preprocedural recanalization (p &lt; 0.001), active smokers had a significantly better postprocedural TIMI flow compared with non-smokers (p &lt; 0.001); this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. Active smokers had a significantly lower in-hospital (p &lt; 0.001) and 30-day (p &lt; 0.001) mortality compared with non-smokers and previous smokers; this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. In conclusion, in our population, active smoking was significantly associated with improved epicardial recanalization and lower in-hospital and 30-day mortality compared with previous and non-smoking history.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30218 - General and internal medicine

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Clinical Medicine

ISSN

2077-0383

e-ISSN

2077-0383

Volume of the periodical

11

Issue of the periodical within the volume

22

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

6722

UT code for WoS article

000887492800001

EID of the result in the Scopus database

2-s2.0-85142347154