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Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitative and Quantitative CEUS Characteristics

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F22%3A00076608" target="_blank" >RIV/65269705:_____/22:00076608 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/22:00126462

  • Result on the web

    <a href="https://www.hindawi.com/journals/cmmi/2022/8229445/" target="_blank" >https://www.hindawi.com/journals/cmmi/2022/8229445/</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1155/2022/8229445" target="_blank" >10.1155/2022/8229445</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitative and Quantitative CEUS Characteristics

  • Original language description

    Objectives. To extend and revise the diagnostic value of contrast-enhanced ultrasonography (CEUS) for differentiation between malignant and benign thyroid nodules. Methods. This single-institution prospective study aims to compare CEUS qualitative and objective quantitative parameters in benign and malignant thyroid nodules. Consecutive cohort of 100 patients was examined by CEUS, 68 out of them were further analysed in detail. All included patients underwent cytological and/or histopathological verification of the diagnosis. Results. Fifty-five (81%) thyroid nodules were benign, and 13 (19%) were malignant. Ring enhancement pattern was strongly associated with a benign aetiology (positive predictive value 100%) and heterogeneous enhancement pattern with malignant aetiology (positive predictive value 72.7%). The shape of the TIC (time-intensity curve) was more often identical in the benign lesion (98.2%) than in malignant lesions (69.2%), p=0.004. Conclusions. This study indicates that CEUS enhancement patterns were significantly different in benign and malignant lesions. Ring enhancement was a very strong indicator of benign lesions, whereas heterogeneous enhancement was valuable to detect malignant lesions.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30224 - Radiology, nuclear medicine and medical imaging

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Contrast Media and Molecular Imaging

  • ISSN

    1555-4309

  • e-ISSN

    1555-4317

  • Volume of the periodical

    2022

  • Issue of the periodical within the volume

    Apr

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    8229445

  • UT code for WoS article

    000822809100002

  • EID of the result in the Scopus database

    2-s2.0-85129503024