Cutoff Values of MASK-air Patient-Reported Outcome Measures
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F23%3A00078246" target="_blank" >RIV/65269705:_____/23:00078246 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S2213219822013150" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S2213219822013150</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jaip.2022.12.005" target="_blank" >10.1016/j.jaip.2022.12.005</a>
Alternative languages
Result language
angličtina
Original language name
Cutoff Values of MASK-air Patient-Reported Outcome Measures
Original language description
BACKGROUND: In clinical and epidemiological studies, cutoffs of patient-reported outcome measures can be used to classify patients into groups of statistical and clinical relevance. However, visual analog scale (VAS) cutoffs in MASK-air have not been tested. OBJECTIVE: To calculate cutoffs for VAS global, nasal, ocular, and asthma symptoms.METHODS: In a cross-sectional study design of all MASK-air participants, we compared (1) approaches based on the percen-tiles (tertiles or quartiles) of VAS distributions and (2) data -driven approaches based on clusters of data from 2 comparators (VAS work and VAS sleep). We then performed sensitivityanalyses for individual countries and for VAS levels corre-sponding to full allergy control. Finally, we tested the different approaches using MASK-air real-world cross-sectional and lon-gitudinal data to assess the most relevant cutoffs.RESULTS: We assessed 395,223 days from 23,201 MASK-air users with self-reported allergic rhinitis. The percentile-oriented approach resulted in lower cutoff values than the data-driven approach. We obtained consistent results in the data-driven approach. Following the latter, the proposed cutoff differenti-ating "controlled" and "partly-controlled" patients was similar to the cutoff value that had been arbitrarily used (20/100). However, a lower cutoff was obtained to differentiate between "partly-controlled" and "uncontrolled" patients (35 vs the arbitrarily-used value of 50/100).CONCLUSIONS: Using a data-driven approach, we were able to define cutoff values for MASK-air VASs on allergy and asthma symptoms. This may allow for a better classification of patients with rhinitis and asthma according to different levels of control, supporting improved disease management. (c) 2022 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:1281-9)
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30200 - Clinical medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Allergy and Clinical Immunology-In Practice
ISSN
2213-2198
e-ISSN
2213-2201
Volume of the periodical
11
Issue of the periodical within the volume
4
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
1281-1289
UT code for WoS article
000999282100001
EID of the result in the Scopus database
2-s2.0-85146860940