Cardiac device-related infective endocarditis need for lead extraction whatever the device according to the ESC EORP EURO-ENDO registry

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F23%3A00078310" target="_blank" >RIV/65269705:_____/23:00078310 - isvavai.cz</a>

Result on the web

<a href="https://academic.oup.com/ehjopen/article/3/4/oead064/7217087" target="_blank" >https://academic.oup.com/ehjopen/article/3/4/oead064/7217087</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/ehjopen/oead064" target="_blank" >10.1093/ehjopen/oead064</a>

Result language

angličtina

Original language name

Cardiac device-related infective endocarditis need for lead extraction whatever the device according to the ESC EORP EURO-ENDO registry

Original language description

Aims Cardiac device-related infective endocarditis (CDRIE) is a severe complication of cardiac device (CD) implantation and is usually treated by antibiotic therapy and percutaneous device extraction. Few studies report the management and prognosis of CDRIE in real life. In particular, the rate of device extraction in clinical practice and the management of patients with left heart infective endocarditis (LHIE) and an apparently non-infected CD (LHIE+CDRIEMINUS SIGN ) are not well described. Methods We sought to study in EURO-ENDO, the characteristics, prognosis, and management of 483 patients with a CD included in and results the European Society of Cardiology EurObservational Research Programme EURO-ENDO registry. Three populations were compared: 280 isolated CDRIE (66.7 +- 14.3 years), 157 patients with LHIE and an apparently non-infected CD (LHIE+CDRIEMINUS SIGN ) (71.1 +- 13.6), and 46 patients with both LHIE and CDRIE (LHIE+CDRIE+) (70.2 +- 10.1). Echocardiography was not always transoesophageal echography (TOE); it was transthoracic echography (TTE) for isolated CDRIE in 88.4% (TOE = 67.6%), for LHIE+CDRIEMINUS SIGN TTE = 93.0% (TOE = 58.6%), and for CDRIE+LHIE+ TTE = 87.0% (TOE = 63.0%). Nuclear imaging was performed in 135 patients (positive for 75.6%). In-hospital mortality was lower in isolated CDRIE 13.2% vs. 22.3% and 30.4% for LHIE+CDRIEMINUS SIGN and LHIE+CDRIE+ (P = 0004). Device extraction was performed in 62.1% patients with isolated CDRIE, 10.2% of LHIE+CDRIEMINUS SIGN patients, and 45.7% of CDRIE+LHIE+ patients. Device extraction was associated with a better prognosis [hazard ratio 0.59 (0.40-0.87), P = 0.0068] even in the LHIE +CDRIEMINUS SIGN group (P = 0.047). Conclusion Prognosis of endocarditis in patients with a CD remains poor, particularly in the presence of an associated LHIE. Although recommended by guidelines, device extraction is not always performed. Device removal was associated with better prognosis, even in the LHIE+CDRIEMINUS SIGN group.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Heart Journal Open

ISSN

2752-4191

e-ISSN

2752-4191

Volume of the periodical

3

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

"oead064"

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85167518810