Clozapine-Associated Myocarditis in a Patient With Poor Metabolism During Fast Titration
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F23%3A00079798" target="_blank" >RIV/65269705:_____/23:00079798 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/23:00130513
Result on the web
<a href="https://journals.lww.com/psychopharmacology/citation/2023/03000/clozapine_associated_myocarditis_in_a_patient_with.20.aspx" target="_blank" >https://journals.lww.com/psychopharmacology/citation/2023/03000/clozapine_associated_myocarditis_in_a_patient_with.20.aspx</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/JCP.0000000000001666" target="_blank" >10.1097/JCP.0000000000001666</a>
Alternative languages
Result language
angličtina
Original language name
Clozapine-Associated Myocarditis in a Patient With Poor Metabolism During Fast Titration
Original language description
To the EditorsSeveral articles concerning clozapine-associated myocarditis have been published in the Journal of Clinical Psychopharmacology . We would like to share our experience with this issue and highlight the rationale for routine monitoring of the markers of myocarditis.Clozapine-associated myocarditis is most likely to occur in the first (84%) or second month (5%) of therapy. It can be started by titration that is too fast for that individual patient. This is supposed to cause the development of clozapine-associated inflammation and cytokine release, further decreasing clozapine clearance (and elevating clozapine plasma level) resulting in increased clozapine-associated inflammation.The importance of metabolization status and titration speed as factors related to clozapine-associated myocarditis has been discussed in prior recent articles.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/LTAB19014" target="_blank" >LTAB19014: Comparison of tolerability and efficacy of 10 Hz and theta burst stimulation protocols of transcranial magnetic stimulation in the treatment of negative symptoms in patients with schizophrenia</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Clinical Psychopharmacology
ISSN
0271-0749
e-ISSN
1533-712X
Volume of the periodical
43
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
2
Pages from-to
186-187
UT code for WoS article
000971626500020
EID of the result in the Scopus database
2-s2.0-85149174805