Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00078435" target="_blank" >RIV/65269705:_____/24:00078435 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/24:00139926
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1111/iwj.14405" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/iwj.14405</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/iwj.14405" target="_blank" >10.1111/iwj.14405</a>

Result language
angličtina
Original language name
Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment
Original language description
The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30216 - Dermatology and venereal diseases

Project
<a href="/en/project/NU21-09-00541" target="_blank" >NU21-09-00541: The role of oxidative stress in the healing of pressure ulcers in patients with spinal cord lesions</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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