Regional anesthesia in neonates with cleft lip and palate: Retrospective study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00079882" target="_blank" >RIV/65269705:_____/24:00079882 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/24:00136436

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0165587624001198?pes=vor" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0165587624001198?pes=vor</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijporl.2024.111965" target="_blank" >10.1016/j.ijporl.2024.111965</a>

Result language

angličtina

Original language name

Regional anesthesia in neonates with cleft lip and palate: Retrospective study

Original language description

Background: Orofacial clefts are the most common congenital abnormalities. Cleft lip reconstruction is performed mostly in 3 months of life including the neonatal period. The consumption of opioids during anesthesia is one of the monitored parameters of anesthesia safety. We investigated the effect of using an infraorbital nerve block for reducing opioid consumption during cleft lip surgery in neonates. Patients/methods: Overall, 100 patients who underwent primary cleft lip surgery in neonatal age between 2018 and 2021 were included in the study. The primary outcome was to compare opioid requirements during cleft lip surgery with and without using regional anesthesia. Secondary outcomes included a first oral intake from surgery between neonates with and without regional anesthesia and complications rate of infraorbital nerve block. Results: Data from 100 patients (46 patients with and 64 without regional anesthesia) were retrospectively analyzed and classified into two groups according to whether regional anesthesia during neonatal cleft lip surgery had been performed or not. The use of infraorbital block was found to be positively correlated with lower doses of opioids used during the general anesthesia for the surgery (mean 0.48 mu g/kg vs 0.29 mu g/kg, p &lt; 0.05). The postoperative course was evaluated based on the interval from surgery to first oral intake which was statistically insignificant shorter (p = 0.16) in the group of patients using regional anesthesia. No complications were recorded in the group of patients with regional anesthesia. Conclusions: Regional anesthesia is associated with reduced opioid consumption during anesthesia thereby increasing the safety of anesthesia in neonates.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30209 - Paediatrics

Project

<a href="/en/project/NU23-06-00301" target="_blank" >NU23-06-00301: Use of modern technology for individualized anesthesiologic management in pediatric patients with orofacial cleft malformation</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Pediatric Otorhinolaryngology

ISSN

0165-5876

e-ISSN

1872-8464

Volume of the periodical

180

Issue of the periodical within the volume

MAY 2024

Country of publishing house

IE - IRELAND

Number of pages

5

Pages from-to

111965

UT code for WoS article

001240156800001

EID of the result in the Scopus database

2-s2.0-85192073093