Prevalence of neurological complications in children hospitalized with SARS-CoV-2 infection or MIS-C in children - single center observational study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00080337" target="_blank" >RIV/65269705:_____/24:00080337 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/24:00136995

Result on the web

<a href="https://www.csnn.eu/casopisy/ceska-slovenska-neurologie/2024-3-8/prevalence-neurologickych-komplikaci-u-deti-hospitalizovanych-s-infekci-sars-cov-2-nebo-mis-c-monocentricka-observacni-studie-138162" target="_blank" >https://www.csnn.eu/casopisy/ceska-slovenska-neurologie/2024-3-8/prevalence-neurologickych-komplikaci-u-deti-hospitalizovanych-s-infekci-sars-cov-2-nebo-mis-c-monocentricka-observacni-studie-138162</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/cccsnn2024213" target="_blank" >10.48095/cccsnn2024213</a>

Result language

angličtina

Original language name

Prevalence of neurological complications in children hospitalized with SARS-CoV-2 infection or MIS-C in children - single center observational study

Original language description

Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused the enduring global COVID-19 pandemic, which has already begun in late 2019. The virus affects various organs, including the nervous system. This study investigates neurological complications in children with COVID-19 or multisystem inflammatory syndrome in children (MIS-C) in the South Moravia region (Czech republic), where a high COVID-19 rate among children (35.790/100.000) allows for a comprehensive analysis. Methods: Data from the University Hospital Brno (from March 2020 to February 2022) were analyzed to study two groups of hospitalized children diagnosed with COVID-19 or MIS-C: one experiencing neurological complications, and the other without neurological symptoms. The analysis included demographics, admission reasons, infection severity and progression, objective neurological findings, hospitalization details, MIS-C presence and therapies used. Descriptive statistics and statistical testing were employed to assess how individual factors influenced neurological complication rates within these groups. Results: Among 420 hospitalized children with COVID-19 or MIS-C, 26 (6.2%) had neurological complications. Preexisting neurological deficits increased the likelihood of worse outcomes (P = 0.0224). Significant differences in hospitalization length (P = 0.0012), infection severity (P = 0.0052), and outcome (P &lt; 0.0001) occurred between groups. Conclusion: Continuous monitoring and further research on neurological complications in children with COVID-19 or MIS-C are crucial for better understanding of the course of the disease and minimize complications after infection.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Česká a slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

1802-4041

Volume of the periodical

87

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

213-219

UT code for WoS article

001296098700001

EID of the result in the Scopus database

2-s2.0-85202810211