Method Comparison for Bone Density in Multiple Myeloma Patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00081381" target="_blank" >RIV/65269705:_____/24:00081381 - isvavai.cz</a>

Alternative codes found

RIV/00216305:26220/24:PU152565 RIV/00843989:_____/24:E0111541

Result on the web

<a href="https://ojs.cvut.cz/ojs/index.php/CTJ/article/view/9984" target="_blank" >https://ojs.cvut.cz/ojs/index.php/CTJ/article/view/9984</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14311/CTJ.2024.3.04" target="_blank" >10.14311/CTJ.2024.3.04</a>

Result language

angličtina

Original language name

Method Comparison for Bone Density in Multiple Myeloma Patients

Original language description

Bone mineral density (BMD) is an important indicator of bone health, particularly in patients with conditions such as multiple myeloma. This study aims to compare three methodologies for quantifying BMD in vertebral regions affected by lytic lesions: two using data from conventional CT with different corrections for tissue composition, and one using data acquired on a dual-energy CT system. Method 1 is based on conventional CT with corrections using reference values for muscle and fat, Method 2 uses conventional CT with corrections based on the measured CT values of paraspinal muscle, and Method 3 is based on dual-energy CT. The Wilcoxon signed-rank test was used for statistical comparison, as the dataset did not follow a normal distribution. The results indicated significant differences between Methods 1 and 2 for BMD in regions of interest (ROIs) within lytic lesions, while no significant differences were found for other comparisons in this group. For vertebrae affected by multiple myeloma, significant differences were found between Methods 1 and 2, and Methods 2 and 3, but not between Methods 1 and 3. In healthy vertebrae, a significant difference was found only between Methods 2 and 3. When all ROIs were combined, significant differences were found between Methods 1 and 2, and Methods 2 and 3, with no difference between Methods 1 and 3. Future research will focus on objectively assessing the accuracy of these methods by comparing their results with a calibration phantom.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Lékař a Technika

ISSN

0301-5491

e-ISSN

—

Volume of the periodical

54

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

94-100

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85213522580