Total pancreatectomy with Langerhans islets autotransplantation for pancreatico-pleural fistula 2 years after pancreatoduodenectomy for chronic pancreatitis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F25%3A00082968" target="_blank" >RIV/65269705:_____/25:00082968 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/25:00085899 RIV/00216224:14110/25:00143572
Result on the web
<a href="https://www.perspinsurg.com/rvch/article/view/1141" target="_blank" >https://www.perspinsurg.com/rvch/article/view/1141</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.48095/ccrvch2025404" target="_blank" >10.48095/ccrvch2025404</a>
Alternative languages
Result language
angličtina
Original language name
Total pancreatectomy with Langerhans islets autotransplantation for pancreatico-pleural fistula 2 years after pancreatoduodenectomy for chronic pancreatitis
Original language description
INTRODUCTION: Pancreaticopleural fistula (PPF) represents a rare complication of chronic pancreatitis. The treatment is complex including pleural drainage, decompression of main pancreatic duct by endoscopic retrograde cholangiopancreatography, pancreas rest with parenteral or enteral nutrition via naso-jejunal feeding tube and somato-statin analogues application. Surgery is indicated when the conservative or endoscopic treat-ment is not successful. In selected cases, total pancreatectomy may be consid-ered. -After these procedures, unstable diabetes mellitus may be a problem. In this case report, the authors present an alternative way to resolve pancreatico-pleural fistula in patients with a history of pancreatic resection. CASE REPORT: A 49-year-old man underwent pancreatoduodenectomy with pancreato-gastrostomy for chronic pancreatitis in 2018. Two years after the procedure, he had severe dyspnea, with X-ray showing left-sided fluidothorax. Pleuracentesis confirmed high amylase activity in pleural effusion. A CT scan was performed and a diag-nosis of pancreaticopleural fistula was made. Due to the failure of conservative treatment, the residual pancreas was resected. The islets of Langerhans from the resected pancreatic tissue were isolated and transplanted back into the patient's liver via the portal vein. The postoperative course was uneventful. Two year after the procedure, the patient was asymptomatic without pleural effusion recurrence and no need of insulin replacement therapy. CONCLUSION: Total pancreatectomy with islet autotransplantation may be an appropri-ate method of treatment for recurrent pancreaticopleural fistula in situations where less radical procedures are not possible.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30212 - Surgery
Result continuities
Project
<a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Rozhledy v chirurgii
ISSN
0035-9351
e-ISSN
1805-4579
Volume of the periodical
104
Issue of the periodical within the volume
9
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
404-408
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-105019113580