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Post-vaccination, post-infection and hybrid immunity against severe cases of COVID-19 and long COVID after infection with SARS-CoV-2 Omicron subvariants, Czechia, December 2021 to August 2023

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985556%3A_____%2F24%3A00597828" target="_blank" >RIV/67985556:_____/24:00597828 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11320/24:10484233 RIV/00216224:14110/24:00137012 RIV/00216208:11120/24:43927495

  • Result on the web

    <a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2024.29.35.2300690" target="_blank" >https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2024.29.35.2300690</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2807/1560-7917.ES.2024.29.35.2300690" target="_blank" >10.2807/1560-7917.ES.2024.29.35.2300690</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Post-vaccination, post-infection and hybrid immunity against severe cases of COVID-19 and long COVID after infection with SARS-CoV-2 Omicron subvariants, Czechia, December 2021 to August 2023

  • Original language description

    Protective effects of immunity against COVID-19 have been shown to diminish over time at varying speed depending on the source of immunity (infection, vaccination or a combination of both), viral variant, age and other factors. Using national-level data from Czechia, we here wanted to assess the protection afforded by vaccines and/or previous infection against severe COVID requiring oxygen support or long COVID up to 16 August 2023.nProtection provided by the original vaccination series wanes fast but can be prolonged through the administration of booster doses, especially with the updated bivalent mRNA vaccines. Immunity after infection or hybrid immunity (from infection and vaccination) provided significantly better protection, waning more slowly over time. The protective effect of vaccines on the development of long COVID in the infected population was small.nVaccination against COVID-19 remains an effective strategy to prevent a severe course of this illness but recent booster doses are required for a significant protection. Since hybrid immunity provides the strongest protection against severe cases, vaccination can be recommended even to individuals who have recovered from the disease. The protective effect of vaccination against long COVID, once infected, appears small.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10102 - Applied mathematics

Result continuities

  • Project

    <a href="/en/project/GF22-10878K" target="_blank" >GF22-10878K: Optimal decision making during pandemics</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Eurosurveillance

  • ISSN

    1025-496X

  • e-ISSN

    1560-7917

  • Volume of the periodical

    29

  • Issue of the periodical within the volume

    35

  • Country of publishing house

    FR - FRANCE

  • Number of pages

    10

  • Pages from-to

    2300690

  • UT code for WoS article

    001308042700002

  • EID of the result in the Scopus database

    2-s2.0-85203081831