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Association Analysis of Arg16Gly Polymorphism of the Beta2-adreneric Receptor Gene in Offspring from Hypertensive and Normotensive Families.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985807%3A_____%2F02%3A06020185" target="_blank" >RIV/67985807:_____/02:06020185 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Association Analysis of Arg16Gly Polymorphism of the Beta2-adreneric Receptor Gene in Offspring from Hypertensive and Normotensive Families.

  • Original language description

    Beta2-adrenergic receptors (beta2AR) can influence BP not only by vasodilation, but also participate in noradrenaline release from sympathetic nerve endings. The frequency of Arg/Arg homozygotes of Arg16Gly polymorphism (PM) of the beta2AR gene was higher in normotensive offspring from hypertensive families. This genotype had higher diastolic BP in control group, a tendency to increased HR in both groups and no relationship to plasma noradrenaline. This PM is involved in predisposition to hypertension.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BB - Applied statistics, operational research

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NA5615" target="_blank" >NA5615: Cytoadhesive molecules as markers of endothelial dysfunction and early atherosclerosis and the possibility of their intervention.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2002

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Blood Pressure

  • ISSN

    0803-7051

  • e-ISSN

  • Volume of the periodical

    11

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    SE - SWEDEN

  • Number of pages

    5

  • Pages from-to

    213-217

  • UT code for WoS article

  • EID of the result in the Scopus database