Basal Ganglia Compensatory White Matter Changes on DTI in Alzheimer’s Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985807%3A_____%2F23%3A00572177" target="_blank" >RIV/67985807:_____/23:00572177 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/23:43925368 RIV/00064173:_____/23:43925368 RIV/00023001:_____/23:00083916
Result on the web
<a href="https://dx.doi.org/10.3390/cells12091220" target="_blank" >https://dx.doi.org/10.3390/cells12091220</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/cells12091220" target="_blank" >10.3390/cells12091220</a>
Alternative languages
Result language
angličtina
Original language name
Basal Ganglia Compensatory White Matter Changes on DTI in Alzheimer’s Disease
Original language description
The volume reduction of the gray matter structures in patients with Alzheimer’s disease is often accompanied by an asymmetric increase in the number of white matter fibers located close to these structures. The present study aims to investigate the white matter structure changes in the motor basal ganglia in Alzheimer’s disease patients compared to healthy controls using diffusion tensor imaging. The amounts of tracts, tract length, tract volume, quantitative anisotropy, and general fractional anisotropy were measured in ten patients with Alzheimer’s disease and ten healthy controls. A significant decrease in the number of tracts and general fractional anisotropy was found in patients with Alzheimer’s disease compared to controls in the right caudate nucleus, while an increase was found in the left and the right putamen. Further, a significant decrease in the structural volume of the left and the right putamen was observed. An increase in the white matter diffusion tensor imaging parameters in patients with Alzheimer’s disease was observed only in the putamen bilaterally. The right caudate showed a decrease in both the diffusion tensor imaging parameters and the volume in Alzheimer’s disease patients. The right pallidum showed an increase in the diffusion tensor imaging parameters but a decrease in volume in Alzheimer’s disease patients.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10103 - Statistics and probability
Result continuities
Project
<a href="/en/project/EF16_019%2F0000766" target="_blank" >EF16_019/0000766: Engineering applications of microworld physics</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cells
ISSN
2073-4409
e-ISSN
2073-4409
Volume of the periodical
12
Issue of the periodical within the volume
9
Country of publishing house
CH - SWITZERLAND
Number of pages
11
Pages from-to
1220
UT code for WoS article
000987033800001
EID of the result in the Scopus database
2-s2.0-85159164367