Improvements in Upper Extremity Isometric Muscle Strength, Dexterity, and Self-Care Independence During the Sub-Acute Phase of Stroke Recovery: An Observational Study on the Effects of Intensive Comprehensive Rehabilitation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985807%3A_____%2F24%3A00599365" target="_blank" >RIV/67985807:_____/24:00599365 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11120/24:43927601 RIV/00216208:11130/24:10485956 RIV/00064190:_____/24:10001287

Result on the web

<a href="https://doi.org/10.3389/fneur.2024.1442120" target="_blank" >https://doi.org/10.3389/fneur.2024.1442120</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fneur.2024.1442120" target="_blank" >10.3389/fneur.2024.1442120</a>

Result language

angličtina

Original language name

Improvements in Upper Extremity Isometric Muscle Strength, Dexterity, and Self-Care Independence During the Sub-Acute Phase of Stroke Recovery: An Observational Study on the Effects of Intensive Comprehensive Rehabilitation

Original language description

BACKGROUND: Stroke often impairs upper extremity motor function, with recovery in the sub-acute phase being crucial for regaining independence. This study examines changes in isometric muscle strength, dexterity, and self-care independence during this period, and evaluates the effects of a comprehensive intensive rehabilitation (COMIRESTROKE). METHODS: Individuals in sub-acute stroke recovery and age- and sex-matched controls were assessed for pre- and post-rehabilitation differences in primary outcomes (grip/pinch strength, Nine Hole Peg Test [NHPT], Action Research Arm Test [ARAT]). COMIRESTROKE’s effects on primary and secondary outcomes (National Institute of Health Stroke Scale [NIHSS], Modified Rankin Scale [MRS], Functional Independence Measure [FIM]) were evaluated. Outcomes were analyzed for dominant and non-dominant limbs, both regardless of impairment and with a focus on impaired limbs. RESULTS: Fifty-two individuals with stroke (NIHSS 7.51 ± 5.71, age 70.25 ± 12.66 years, 21.36 ± 12.06 days post-stroke) and forty-six controls participated. At baseline, individuals with stroke showed significantly lower strength (dominant grip, key pinch, tip-tip pinch, padj < 0.05), higher NHPT scores (padj < 0.05), and lower ARAT scores (padj < 0.001). COMIRESTROKE led to improvements in dominant key pinch, non-dominant tip-tip pinch, NHPT, and both dominant and non-dominant ARAT (padj < 0.05). Notably, non-dominant key pinch improved significantly when considering only impaired hands. Pre- and post-test differences between groups were significant only for ARAT (both limbs), even after adjustment (padj < 0.05). All secondary outcomes (NIHSS, MRS, FIM) showed significant improvement post-COMIRESTROKE (padj < 0.001). CONCLUSION: Individuals with stroke exhibit reduced muscle strength and dexterity, impairing independence. However, comprehensive intensive rehabilitation significantly improves these functions. Data are available from the corresponding author upon request and are part of a sub-study of NCT05323916.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10103 - Statistics and probability

Project

<a href="/en/project/EH22_008%2F0004583" target="_blank" >EH22_008/0004583: Research of Excellence on Digital Technologies and Wellbeing</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in Neurology

ISSN

1664-2295

e-ISSN

1664-2295

Volume of the periodical

15

Issue of the periodical within the volume

October 2024

Country of publishing house

CH - SWITZERLAND

Number of pages

10

Pages from-to

1442120

UT code for WoS article

001350113500001

EID of the result in the Scopus database

2-s2.0-85208612468