Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F01%3A20010274" target="_blank" >RIV/67985823:_____/01:20010274 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Early changes in extrafusal and intrafusal muscle fibers following heterochronous isotransplantation.

Original language description

The ultrastructure of regenerating intrafusal and extrafusal fibres was studied 18 hours to 30 days after heterochronous isotransplantation, when bupivacaine-treated EDL or soleus muscles from early postnatal rats were intramuscularly grafted into EDL muscles of adult inbred recipients. Similarly as in other models of mammalian muscle regeneration, surviving satellite cells gave rise to presumptive myoblasts multiplying within the preserved basal lamina tubes at day 4 after grafting, myoblasts fused toform myotubes with central myonuclei by day 6 after grafting. Extrafusal myotubes differentiated into thin muscle fibres by day 8, which progressively increased in diameter and their nuclei became localized subsarcolemmally from day 13 onwards. The basallaminae of some intrafusal fibres already contained one or more nascent myotubes by day 4 after grafting. Regenerated intrafusal fibres lacked the typical nuclear accumulations and their number varied from 1 to 8 fibres per spindle; addi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/GA304%2F00%2F1653" target="_blank" >GA304/00/1653: Regulation of muscle fibre phenotype expression by thyroid hormones</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Neuropathologica

ISSN

0001-6322

e-ISSN

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Volume of the periodical

102

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

12

Pages from-to

473-484

UT code for WoS article

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EID of the result in the Scopus database

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