Genome scanning of the HXB/BXH sets of recombinant inbred strains of the rat for quantitative trait loci associated with conditioned taste aversion
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F02%3A02" target="_blank" >RIV/67985823:_____/02:02 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/02:00002297 RIV/67985823:_____/02:00142282
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Genome scanning of the HXB/BXH sets of recombinant inbred strains of the rat for quantitative trait loci associated with conditioned taste aversion
Original language description
A genome scanning for QTL associated with CTA was performed in the HXB/BXH sets of recombinant inbred (RI) strains derived from the Brown Norway (BN-Lx) rat and the spontaneously hypertensive rat (SHR). The BN-Lx progenitor showed a significantly stronger CTA (8.3+2.8%) than the SHR progenitor (27.8+3.3%, p<0.0001). The distribution of CTA values among RI strains was continuous suggesting a polygenic mode of inheritance. Genome scanning of RI strains with more than 700 gene markers revealed a significant association of CTA with the D2Cebr11s4 marker on chromosome 2 (LRS = 18.7). This finding was confirmed by detecting a significant difference in CTA between the SHR progenitor and the SHR-2 (SHR.BN-D2Rat171/D2Arb24) congenic strain that are geneticallyidentical except for a segment of chromosome 2 that was transferred onto the genetic background of the SHR from the BN strain.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NF4795" target="_blank" >NF4795: Genetic and correlation analysis of learning and memory processies in the art.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Behavior Genetics
ISSN
0001-8244
e-ISSN
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Volume of the periodical
31
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
51-56
UT code for WoS article
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EID of the result in the Scopus database
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