The dorsal column pathway facilitates visceromotor responses to colorectal distention after colon inflammation in rats.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F03%3A20030090" target="_blank" >RIV/67985823:_____/03:20030090 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The dorsal column pathway facilitates visceromotor responses to colorectal distention after colon inflammation in rats.
Original language description
We examined the effect of bilateral dorsal columns (DC) or ventrolateral (VL) spinal cord lesions on viscemotor reflex EMG activity evoked by graded colorectal distention under control conditions and after colon inflammation with mustard oil. Our resultssuggest that the role of the DC pathway in transmission of visceral pain is augmented under inflammatory conditions when symptoms of visceral allodynia and hyperalgesia may be present. The VL lesions eliminated the viscemotor reflex, presumably by interrupting a facilitatory pathway that involves the brain stem.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
<a href="/en/project/GA309%2F03%2F0752" target="_blank" >GA309/03/0752: Cellular and molecular mechanisms of nociception at spinal cord level.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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