Polymer vesicles in vivo: correlations with PEG molecular weight.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F03%3A20030093" target="_blank" >RIV/67985823:_____/03:20030093 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Polymer vesicles in vivo: correlations with PEG molecular weight.

Original language description

Nanovesicles made from PEG-based block copolymers were injected into rats and found to have circulation times about two-fold longer than PEGylated, or Stealth, liposomes. After opsonization with plasma proteins, they were cleared by macrophages and uptaken by various organs, mainly liver and spleen. They did not exert toxic effects on endothelial and smooth muscle cells in culture. They could be used as carriers for controlled drug delivery.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EI - Biotechnology and bionics

OECD FORD branch

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Project

<a href="/en/project/IAA7011908" target="_blank" >IAA7011908: Improved cell adhesion on physico-chemically modified polymer surfaces</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Controlled Release

ISSN

0168-3659

e-ISSN

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Volume of the periodical

90

Issue of the periodical within the volume

3

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

12

Pages from-to

323-334

UT code for WoS article

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EID of the result in the Scopus database

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