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Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F06%3A00050754" target="_blank" >RIV/67985823:_____/06:00050754 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors

  • Original language description

    Replacement of certain amino acids in the o3 loop of M3 receptor for corresponding amino acids from M2 receptor induce changes in cooperativity between strychnin-like allosteric modulators and N-methylscopolamine. These changes are always towards more positive values

  • Czech name

    Determinanty pozitivní kooperativity mezi strychninu podobnými alosterickými modulátory a N-metylskopolaminem u muskarinových receptorů

  • Czech description

    Náhrada určitých aminokyselin ve třetí extracelulární kličce M3 receptoru za odpovídající aminokyseline z M2 receptoru vyvolává změny v kooperativitě mezi strychninu podobnými alosterickými modulátory a N-metylskopolaminem. Tyto změny směřují vždy k pozitivnějším hodnotám

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Molecular Neuroscience

  • ISSN

    0895-8696

  • e-ISSN

  • Volume of the periodical

    30

  • Issue of the periodical within the volume

    1-2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    2

  • Pages from-to

    111-112

  • UT code for WoS article

  • EID of the result in the Scopus database