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Pregnenolone sulfate modulation of N-methyl-d-aspartate receptors is phosphorylation dependent

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F09%3A00328948" target="_blank" >RIV/67985823:_____/09:00328948 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388963:_____/09:00328948

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Pregnenolone sulfate modulation of N-methyl-d-aspartate receptors is phosphorylation dependent

  • Original language description

    The modulation of native and recombinant NMDA receptors function by pregnenolone sulfate (PS) was studied by patch-clamp measurements. The rate of the diminution of NMDA receptors potentiation by PS in isolated membrane patches was influenced by inhibitors of protein phosphatases and kinases. The results suggest that the PS-potentiating effect at NMDA receptors is connected to the cellular phosphorylation/dephosphorylation pathways

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neuroscience

  • ISSN

    0306-4522

  • e-ISSN

  • Volume of the periodical

    160

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    13

  • Pages from-to

  • UT code for WoS article

    265722100005

  • EID of the result in the Scopus database