Selective Inhibition of Casein Kinase 1 epsilon Minimally Alters Circadian Clock Period
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F09%3A00328977" target="_blank" >RIV/67985823:_____/09:00328977 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Selective Inhibition of Casein Kinase 1 epsilon Minimally Alters Circadian Clock Period
Original language description
Casein kinases 1 (CK1) epsilon and delta mutations have dramatic effect on circadian clock period. We have previously shown, that pan-CK1delta/epsilon inhibitor causes a delay in animal models of circadian rhythm, however it remains unclear, whether oneof the kinases has predominant role. Here we have used novel selective CK1 epsilon inhibitor to show that wild-type CK1 epsilonhas only minimal effect on circadian clock relative to CK1 delta
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Pharmacology and Experimental Therapeutics
ISSN
0022-3565
e-ISSN
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Volume of the periodical
330
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
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UT code for WoS article
268150900007
EID of the result in the Scopus database
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