Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F09%3A00329481" target="_blank" >RIV/67985823:_____/09:00329481 - isvavai.cz</a>
Alternative codes found
RIV/67179843:_____/09:00329481 RIV/67179843:_____/09:00341140 RIV/60076658:12640/09:00010038
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel
Original language description
In this study we used scanning mutagenesis of the residues within the putative inner pore S6 region of TRPA1 channel with the aim of understanding the process of TRPA1 activation. We identify residues proline 949, asparagine 954 and glycine?(X)3-glycinemotif as structural determinants of TRPA1 activation and deactivation and these findings contribute to our better understanding of molecular mechanisms of pain sensation
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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