Glycerol-3-phosphate Dehydrogenase Expression and Oxygen Consumption in Liver Mitochondria of Female and Male Rats with Chronic Alteration of Thyroid Status
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F11%3A00359114" target="_blank" >RIV/67985823:_____/11:00359114 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1055/s-0030-1265220" target="_blank" >http://dx.doi.org/10.1055/s-0030-1265220</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/s-0030-1265220" target="_blank" >10.1055/s-0030-1265220</a>
Alternative languages
Result language
angličtina
Original language name
Glycerol-3-phosphate Dehydrogenase Expression and Oxygen Consumption in Liver Mitochondria of Female and Male Rats with Chronic Alteration of Thyroid Status
Original language description
In our chronic experiments the activity and protein amount of glycerol-3-phosphate dehydrogenase (GPDH) in mitochondria isolated from the liver of adult male and female inbred Lewis strain euthyroid (EU), hyperthyroid (TH) and hypothyroid (HY) rats wereanalyzed by biochemical and Western blot methods. The TH status led to a significant increase and HY status to a significant decrease of enzyme activity and protein amount in both male and female animals. These changes were, however, more pronounced in females. Measurements of serum thyroid hormone levels and analysis of anatomical parameters confirmed that our procedures inducting the TH and HY states are efficient and reliable and that determination of GPDH can serve as an additional criterion for theevaluation of the thyroid hormone status
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Hormone and Metabolic Research
ISSN
0018-5043
e-ISSN
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Volume of the periodical
43
Issue of the periodical within the volume
1
Country of publishing house
DE - GERMANY
Number of pages
5
Pages from-to
43-47
UT code for WoS article
000285914900008
EID of the result in the Scopus database
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