Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F12%3A00377129" target="_blank" >RIV/67985823:_____/12:00377129 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1038/ijo.2011.87" target="_blank" >http://dx.doi.org/10.1038/ijo.2011.87</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/ijo.2011.87" target="_blank" >10.1038/ijo.2011.87</a>

Result language
angličtina
Original language name
Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control
Original language description
Compared with males of the C57BL/6N strain, female mice demonstrate increased capacity for adipocyte enlargement in response to a long-term HF feeding, which is associated with reduced adipose tissue macrophage infiltration and lower fat deposition in the liver, and with better insulin sensitivity. Our data suggest that adipose tissue expandability linked to adiponectin secretion might have a role in the sex differences observed in obesity-associated metabolic disorders
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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