New Insight on the Mechanisms of Epileptogenesis in the Developing Brain

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F12%3A00390006" target="_blank" >RIV/67985823:_____/12:00390006 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-7091-1360-8_1" target="_blank" >http://dx.doi.org/10.1007/978-3-7091-1360-8_1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-7091-1360-8_1" target="_blank" >10.1007/978-3-7091-1360-8_1</a>

Result language
angličtina
Original language name
New Insight on the Mechanisms of Epileptogenesis in the Developing Brain
Original language description
The incidence of epilepsy is at its highest in childhood and seizures can persist for a lifetime. As brain tissue from pediatric patients with epilepsy is rarely available, the analysis of molecular and cellular changes during epileptogenesis, which could serve as targets for treatment approaches, has to rely largely on the analysis of tissue from animal models. However, these data have to be analyzed in the context of the developmental stage when the insult occurs. Here we review the current status ofthe available animal models, the molecular analysis done in these models, as well as treatment attempts to prevent epileptogenesis in the immature brain
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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