Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00392087" target="_blank" >RIV/67985823:_____/13:00392087 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00395-012-0316-y" target="_blank" >http://dx.doi.org/10.1007/s00395-012-0316-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00395-012-0316-y" target="_blank" >10.1007/s00395-012-0316-y</a>

Result language
angličtina
Original language name
Mapping genetic determinants of coronary microvascular remodeling in the spontaneously hypertensive rat
Original language description
To uncover possible genetic determinants of coronary microvascular remodeling, we carried out detailed histological and histomorphometric analysis of the heart and coronary vasculature in 30 weeks old SHR, age-matched Brown Norway (BN-Lx) parentals and BXH/HXB recombinant inbred (RI) strains. Using previously mapped expression quantitative trait loci (eQTLs), we carried out a genomewide association analysis and identified genetic determinants of cardiac gene expression and histomorphometric traits
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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