Increased Sensitivity of the Circadian System to Temporal Changes in the Feeding Regime of Spontaneously Hypertensive Rats - A Potential Role for Bmal2 in the Liver

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00396915" target="_blank" >RIV/67985823:_____/13:00396915 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0075690" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0075690</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0075690" target="_blank" >10.1371/journal.pone.0075690</a>

Result language
angličtina
Original language name
Increased Sensitivity of the Circadian System to Temporal Changes in the Feeding Regime of Spontaneously Hypertensive Rats - A Potential Role for Bmal2 in the Liver
Original language description
Sensitivity of the circadian system to temporal change in feeding regime is higher in spontaneously hypertensive rats (SHR) than in controls. At the behavioral level, SHR develop faster food anticipatory activity than control rats and shift completely their locomotor activity rhythm. At the molecular level, their peripheral clock in the liver exhibits larger phase shift due to the change in feeding regime. The results suggested possible involvement of Bmal2 gene in the higher sensitivity of the SHR hepatic clock to the metabolic challenge
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—

Project
<a href="/en/project/GAP303%2F11%2F0668" target="_blank" >GAP303/11/0668: Insight into the circadian system of the spontaneously hypertensive rat (SHR) during ontogenesis and in adulthood</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)