Oxidative stress in immature brain following experimentally-induced seizures

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00422469" target="_blank" >RIV/67985823:_____/13:00422469 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Oxidative stress in immature brain following experimentally-induced seizures

Original language description

Status epilepticus (SE) induced in immature rats is associated with oxidative stress and mitochondrial dysfunction. Oxidative stress is apparently due to both the increased free radicals production and the limited antioxidant defense. Pronounced inhibition of mitochondrial complex I activity was demonstrated already during the acute phase of SE and it persists during long periods of survival following SE. The findings suggest that oxidative modification of the enzyme is most likely responsible for the sustained deficiency of complex I activity

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

62

Issue of the periodical within the volume

Suppl.1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

10

Pages from-to

"S39"-"S48"

UT code for WoS article

000328901900004

EID of the result in the Scopus database

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