ROS production in brown adipose tissue mitochondria: The question of UCP1-dependence

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F14%3A00437819" target="_blank" >RIV/67985823:_____/14:00437819 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.bbabio.2014.04.005" target="_blank" >http://dx.doi.org/10.1016/j.bbabio.2014.04.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bbabio.2014.04.005" target="_blank" >10.1016/j.bbabio.2014.04.005</a>

Result language
angličtina
Original language name
ROS production in brown adipose tissue mitochondria: The question of UCP1-dependence
Original language description
Whether active UCP1 can reduce ROS production in brown-fat mitochondria is presently not settled. The significance of UCP1 for ROS production was studied by comparing the ROS production in brown-fat mitochondria isolated from wildtype mice or from UCP1(/) knockout mice. Only ROS production supported by exogenously added succinate was affected by the presence of active UCP1; ROS production supported by any other tested substrate was unaffected. In conclusion, UCP1 activity does not generally diminish ROSproduction in brown-fat mitochondria
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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