Zygosaccharomyces rouxii Trk1 is an efficient potassium transporter providing yeast cells with high lithium tolerance

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00445013" target="_blank" >RIV/67985823:_____/15:00445013 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1093/femsyr/fov029" target="_blank" >http://dx.doi.org/10.1093/femsyr/fov029</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/femsyr/fov029" target="_blank" >10.1093/femsyr/fov029</a>

Result language

angličtina

Original language name

Zygosaccharomyces rouxii Trk1 is an efficient potassium transporter providing yeast cells with high lithium tolerance

Original language description

Zygosaccharomyces rouxii is an osmotolerant yeast and is endowed with only one typical potassium transporter (ZrTrk1). We characterized ZrTrk1 activity and its contribution to various physiological parameters in detail. Our results show that ZrTrk1 is ahigh-affinity K+ transporting system efficiently discriminating between K+ and Li+. Upon ZrTrk1 heterologous expression in S. cerevisiae, it confers cells with a remarkably high lithium tolerance due to preventing Li+ influx into cells, it is able to complement a plasma-membrane hyperpolarization and a decrease in intracellular pH caused by the lack of endogenous K+ transporting systems. Our data corroborate a tight connection between potassium and proton transporters in yeasts and provides new insightsinto Z. rouxii cation homeostasis and the basis of its high osmotolerance

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

—

Project

<a href="/en/project/GAP503%2F10%2F0307" target="_blank" >GAP503/10/0307: Molecular basis of osmotolerant yeast Z. rouxii, Z. bailii and D. hansenii specific properties and their biotechnological applications</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

FEMS Yeast Research

ISSN

1567-1356

e-ISSN

—

Volume of the periodical

15

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

—

UT code for WoS article

000357878100015

EID of the result in the Scopus database

2-s2.0-84949197438