Dietary uptake of omega-3 fatty acids in mouse tissue studied by time-of-flight secondary ion mass spectrometry (TOF-SIMS)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00446422" target="_blank" >RIV/67985823:_____/15:00446422 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1007/s00216-015-8515-7" target="_blank" >http://dx.doi.org/10.1007/s00216-015-8515-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00216-015-8515-7" target="_blank" >10.1007/s00216-015-8515-7</a>

Result language

angličtina

Original language name

Dietary uptake of omega-3 fatty acids in mouse tissue studied by time-of-flight secondary ion mass spectrometry (TOF-SIMS)

Original language description

The uptake of omega-3 fatty acids and their incorporation in specific lipids were studied in adipose, skeletal muscle, and liver tissues of mice given high-fat diets with or without omega-3 supplements in the form of phospholipids or triglycerides usingtime-of-flight secondary ion mass spectrometry (TOF-SIMS). The results demonstrate significant uptake of EPA and DHA, and the incorporation of these fatty acids in specific lipid molecules, in all three tissue types in response to the dietary omega-3 supplements. Moreover, the results indicate reduced concentrations of arachidonic acid (AA) and depletion of lipids containing AA in tissue samples from mice given supplementary omega-3, as compared to the control mice. The effect on the lipid composition,in particular the DHA uptake and AA depletion, was found to be significantly stronger when the omega-3 supplement was supplied in the form of phospholipids, as compared to triglycerides

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/GA14-09347S" target="_blank" >GA14-09347S: The role of endocannabinoid system in metabolic effects of marine omega-3 phospholipids</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Analytical and Bioanalytical Chemistry

ISSN

1618-2642

e-ISSN

—

Volume of the periodical

407

Issue of the periodical within the volume

17

Country of publishing house

DE - GERMANY

Number of pages

11

Pages from-to

5101-5111

UT code for WoS article

000356461800020

EID of the result in the Scopus database

2-s2.0-84939245081