Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F16%3A00464967" target="_blank" >RIV/67985823:_____/16:00464967 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1162/NECO_a_00880" target="_blank" >http://dx.doi.org/10.1162/NECO_a_00880</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1162/NECO_a_00880" target="_blank" >10.1162/NECO_a_00880</a>

Result language
angličtina
Original language name
Presynaptic Spontaneous Activity Enhances the Accuracy of Latency Coding
Original language description
The time to the first spike after stimulus onset typically varies with the stimulation intensity. Experimental evidence suggests that neural systems use such response latency to encode information about the stimulus. We investigate the decoding accuracy of the latency code in relation to the level of noise in the form of presynaptic spontaneous activity. Paradoxically, the optimal performance is achieved at a nonzero level of noise and suprathreshold stimulus intensities. We argue that this phenomenon results from the influence of the spontaneous activity on the stabilization of the membrane potential in the absence of stimulation. The reported decoding accuracy improvement represents a novel manifestation of the noise-aided signal enhancement.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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