Peptide analysis of tooth enamel A sex estimation tool for archaeological, anthropological, or forensic research

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F23%3A00574565" target="_blank" >RIV/67985823:_____/23:00574565 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/23:10465891 RIV/00216275:25310/23:39920291
Result on the web
<a href="https://doi.org/10.1002/jssc.202300183" target="_blank" >https://doi.org/10.1002/jssc.202300183</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jssc.202300183" target="_blank" >10.1002/jssc.202300183</a>

Result language
angličtina
Original language name
Peptide analysis of tooth enamel A sex estimation tool for archaeological, anthropological, or forensic research
Original language description
Proteomics has become an attractive method to study human and animal material, biological profile, and origin as an alternative to DNA analysis. It is limited by DNA amplification in ancient samples and its contamination, high cost, and limited preservation of nuclear DNA. Currently, three approaches are available to estimate sex-osteology, genomics, or proteomics, but little is known about the relative reliability of these methods in applied settings. Proteomics provides a new, seemingly simple, and relatively non-expensive way of sex estimation without the risk of contamination. Proteins can be preserved in hard teeth tissue (enamel) for tens of thousands of years. It uses two sexually distinct forms of the protein amelogenin in tooth enamel detectable by liquid chromatography-mass spectrometry, the protein amelogenin Y isoform is present in enamel dental tissue only in males, while amelogenin isoform X can be found in both sexes. From the point of view of archaeological, anthropological, and forensic research and applications, the reduced destruction of the methods used is essential, as well as the minimum requirements for sample size.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry

Project
<a href="/en/project/GA20-03899S" target="_blank" >GA20-03899S: Affinity capillary electrokinetic methods for selective analysis of biopolymers and metabolites and for study of their interactions</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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