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Cardiac cachexia is associated with altered expression of genes related to iron and lipid metabolism

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F23%3A00583471" target="_blank" >RIV/67985823:_____/23:00583471 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023001:_____/23:00084304

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1111/eci.13992" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/eci.13992</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cardiac cachexia is associated with altered expression of genes related to iron and lipid metabolism

  • Original language description

    Deeper lipidomic analysis in EAT uncovered potential higher oxidation of polyunsaturated lipids in cachexia. Analysis of significantly regulated phosphatidyl ethanolmanines revealed higher content of arachidonic acid at sn2 position. Changes in iron and lipid metabolism in both EAT and MYO can be key markers of cardiac cachexia, they are more pronounced in EAT, and suggest the role of EAT-MYO microenvironment in the development of HF.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

    <a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů