Tips and tricks for LC–MS-based metabolomics and lipidomics analysis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F24%3A00598398" target="_blank" >RIV/67985823:_____/24:00598398 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.trac.2024.117940" target="_blank" >https://doi.org/10.1016/j.trac.2024.117940</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.trac.2024.117940" target="_blank" >10.1016/j.trac.2024.117940</a>

Result language
angličtina
Original language name
Tips and tricks for LC–MS-based metabolomics and lipidomics analysis
Original language description
Metabolomics and lipidomics are rapidly growing fields, leading to novel discoveries and advancing the understanding of biological processes at the molecular level. However, designing a proper workflow and choosing from countless options can be challenging, especially for beginners in the field. To address this challenge, we provide a comprehensive overview of metabolomics and lipidomics tools and a step-by-step guide that includes “tips and tricks” based on current metabolomics and lipidomics analysis approaches. We include power analysis, sample collection and preparation, separation and detection of metabolites using primarily liquid chromatography–mass spectrometry (LC–MS), processing of raw instrumental files, quality control, statistical analysis, and data sharing. This guide offers practical insights applicable to diverse research areas, covering all the essential steps in metabolomic and lipidomic profiling.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)