Supercritical Fluid Extraction of Cynaropicrin and 20-Hydro.xyecdysone from Leuzea carthamoides DC

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F08%3A00307375" target="_blank" >RIV/67985858:_____/08:00307375 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/08:00109264

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Supercritical Fluid Extraction of Cynaropicrin and 20-Hydro.xyecdysone from Leuzea carthamoides DC

Original language description

Leuzea carthamoides is an adaptogenic plant containing biologically active compounds as ecdysteroids and guaianolide-type sesquiterpene lactones, conventionally extracted from the plant with ethanol. Ethanol-modified near-critical CO2 was used as selective solvent with the aim to increase the level of 20-hydroxyecdysone (20E) in the extract from L. carthamoides roots and to remove selectively cynaropicrin, a sesquiterpene lactone of bitter taste, from the leaves. The extraction conditions were varied (pressure 20-28 MPa, temperature 40-60 ?C, ethanol concentration in the solvent 0-7.1 %) and the extraction yield and extract composition were compared with the results of ethanol extraction. Cynaropicrin was quantitatively removed from the leaves where 89% of 20E was retained. The extraction yield of 20E from roots with ethanol-modified CO2 was by 30 % lower than with ethanol but its concentration in the extract was by 67 % higher.

Czech name

Superkriticlá extrakce cynaropikrinu a 20-hydroxyekdysonu z parchy saflorové

Czech description

Adaptogenní rostlina Leuzea carthamoides obsahuje biologicky aktivní látky jako ekdysteroidy a seskviterpenické laktony, které se z rostliny extrahují etanolem. S cílem zvýšit koncentraci 20-hydroxyekdysonu (20E) v extraktu z kořenů a odstranit z listů cynaropikrin, hořký seskviterpenický lakton, byl v této práci jako rozpouštědlo použit etanolem modifikovaný superkritický CO2. Extrakční podmínky byly tlak 20-28 MPa, teplota 40-60 ?C, koncentrace EtOH v CO2 0-7.1 %. Cynaropikrin byl kvantitativně odstraněn z listů, kde zůstalo 89 % 20E. Výtěžek 20E z kořenů byl sice o 30 % nižší než při konvenční extrakci EtOH, ale jeho koncentrace v extraktu byla o 67 % vyšší.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CI - Industrial chemistry and chemical engineering

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

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Volume of the periodical

31

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

1387-1392

UT code for WoS article

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EID of the result in the Scopus database

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